What is the drug selegiline used for?

Selegiline is used in combination with levodopa or levodopa and carbidopa combination to treat Parkinson’s disease (sometimes called “shaking palsy” or “paralysis agitans”). This medicine works to increase and extend the effects of levodopa, and may help to slow the progress of Parkinson’s disease.

How does selegiline make you feel?

Dizziness, abdominal pain, dry mouth, nausea, stomach upset, trouble sleeping, and headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. If you are also taking levodopa, you may experience more side effects from the levodopa when taking selegiline.

What are the side effects of selegiline?

Side Effects

• Dizziness, abdominal pain, dry mouth, nausea, stomach upset, trouble sleeping, and headache may occur.
• If you are also taking levodopa, you may experience more side effects from the levodopa when taking selegiline.

Is selegiline a good antidepressant?

Transdermal selegiline, an irreversible selective monoamine oxidase B (MAO-B) inhibitor, is approved as an antidepressant in the USA. Some reports have shown that oral selegiline treatment can also be effective in treating depression.

Does selegiline affect sleep?

Before the introduction of selegiline, the patients did not complain of their sleep during the night, but of involuntary falling asleep or of excessive sleepiness during the day; about this latter, 30 of our 45 patients showed an ESS score higher than 10.

What should I avoid while using selegiline?

Foods that have a high tyramine content (most common in foods that are aged or fermented to increase their flavor), such as cheeses, fava or broad bean pods, yeast or meat extracts, smoked or pickled meat, poultry, or fish, fermented sausage (bologna, pepperoni, salami, summer sausage) or other fermented meat.

Does selegiline help with anxiety?

These results indicate that selegiline has antidepressant and mild anxiolytic effects in CD157 KO mice, and suggest that it is an effective antiparkinsonian drug for depressive and anxiety symptoms in PD patients with a CD157 single nucleotide polymorphism (SNP).

What foods should you avoid when taking selegiline?

What should I avoid while taking selegiline?

• air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring;
• any spoiled or improperly stored beef, poultry, fish, or liver;
• beer from a tap, beer that has not been pasteurized;

Does selegiline give you energy?

Increased energy was reported at doses greater than 10 mg per day.

How long does it take selegiline to work?

Selegiline is the only FDA-approved treatment for canine cognitive dysfunction. Although the onset of action can be variable (between four and12 weeks), most dogs show some improvement after one month of treatment and there may be continued improvement over time.

Does selegiline affect blood pressure?

Selegiline therapy was associated with orthostatic hypotension on tilting at 10 minutes and lesser hypotension on tilting for 2 minutes and standing. On tilting for 10 minutes, six patients on selegiline developed symptomatic hypotension and in five the blood pressure fell to below 100 mm Hg.