What is Adagen used for?

ADAGEN® (pegademase bovine) Injection is a modified enzyme used for enzyme replacement therapy for the treatment of severe combined immunodeficiency disease (SCID) associated with a deficiency of adenosine deaminase.

What is ADA Injection?

Adenosine deaminase (ADA) deficiency can be treated by bone marrow transplantation, or by enzyme replacement therapy, in which functional ADA is given to the patient by injection.

What does PEG ADA stand for?

adenosine deaminase conjugated with polyethylene glycol Abbreviation: PEG-ADA. A cytoplasmic enzyme used to treat severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency.

What are the 2 components of PEG ADA?

PEG-Adenosine deaminase (Adagen®) and PEG-asparaginase (Oncaspar®) are two bioconjugates approved by the FDA for the treatment of severe combined immunodeficiency disease (in the case of the former) and acute lymphoblastic leukemia and other lymphoid malignancies (in the case of the latter).

What is ADA test for TB?

The adenosine deaminase (ADA) test is not a diagnostic test, but it may be used along with other tests such as pleural fluid analysis, acid-fast bacillus (AFB) smear and culture, and/or tuberculosis molecular testing to help determine whether a person has a Mycobacterium tuberculosis infection (tuberculosis or TB) of …

What is ADA normal range?

Receiver Operating Characteristic (ROC) curves were used to determine a cutoff value for the ADA test. A test value below 4.0 was considered to be normal and above 4.0 to be abnormal.

What is the normal range of ADA in pleural fluid?

Pleural fluid ADA level was more than 36 IU/L in cases of tubercular pleural effusion. It ranged 36 to 229.7 IU/L. While in case of malignancy it was more than 18.5 IU/L (18.5 to 87.6 IU/L). In one case of hypoproteinemia it was 9.21 IU/L.